Spot on tidbit from Seattle’s own James Callan: develop your site with content in mind from the beginning, but don’t be so strict as to expect finalized web content before design begins.
“Content first vs. content from the beginning: Is it semantics? Maybe.
But it matters. I’ve seen a number of people who interpret “content first” as “you need final copy before the designer can start working,” which is wrong. And claiming firsties is the kind of behavior you expect from blog commenters, not web professionals.”